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Reviewed by: Cheryl LaGuardia, Research Librarian, Widener Library, Harvard University
Biology of Sex Differences is published by BioMed Central Ltd., which makes it a journal that anyone interested in any aspect of the effects of sex on biology and disease will want to consult. As the journal’s Aims nd Scope page notes, “Sex has profound effects on physiology and the susceptibility to disease. The function of cells and organs depends on their sex, determined by the interplay among the genome and biological and social environments. The study of sex differences is a discipline in itself, with its own concepts and methods that apply across tissues.”
The page further states that “an understanding of the effect of sex on biology and disease requires an interdisciplinary approach in which the interaction of diverse sex-specific factors are studied at all levels, from molecular to the level of biological systems. The development of novel therapies for disease requires a sex-based conceptual framework.” Thus the journal’s scope covers material about sex differences in clinical studies bearing on sex differences in disease or response to therapy; epigenetics; the genome; the interaction of tissue systems, in any system including adipose, behavioral, cardiovascular, immune, muscular, neural, renal, and skeletal; molecular and cell biology; physiology; and tissue biology.
BSD publishes six different types of articles: Book reviews, Commentaries, Databases, Letters to the Editor, Research articles, and Review articles. It is searchable by keyword, citation, and volume, and is indexed in CAS, PubMed and PubMed Central, Science Citation Index Expanded, SCOPUS, and the Zoological Record, among other indexes. Like other BioMed Central journals, BSD boasts an extraordinary, global group of individuals on its Editorial Board, To publish in the hybrid OA Biology of Sex Differences article-processing charges of £1565/$2450/€1995 for each article must be paid by the author (or sponsoring institution), with discounts available and fees waived for authors from low-income countries.
The most recent volume of BSD available, volume 7 for 2016, holds 68 articles thus far. They include the review article, “A primer on the use of mouse models for identifying direct sex chromosome effects that cause sex differences in non-gonadal tissues,” the research article, “Sex-specific differences in fetal and infant growth patterns: a prospective population-based cohort study,” a letter to the editor, “The p.R92W variant of NR5A1/Nr5a1 induces testicular development of 46,XX gonads in humans, but not in mice: phenotypic comparison of human patients and mutation-induced mice,” the commentary, “Instructional design framework for the sex and gender-specific health multimedia case-based learning modules,” and the research article, “Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development.” This is a scholarly journal that will be useful to researchers studying sex difference biology, and should be made readily available to them.