• Full Text
    • Scholarly Journal

    Sustainable analysis of COVID-19 Co-packaged paxlovid: exploring advanced sampling techniques and multivariate processing tools

    ; 
    ; 
    ; 
    . 
    ; London Vol. 19, Iss. 1,  (Dec 2025): 206.     DOI:10.1186/s13065-025-01567-2
    PDF CiteCite
    Copy URLPrintAll Options

    References (61)

    • 1.
      Haddad R, El, Fakhereddine R, Lécot C, Venkiteswaran G. Extended Latin Hypercube Sampling for Integration and Simulation. In: Springer Proceedings in Mathematics and Statistics. Springer, Berlin, Heidelberg; 2013. p. 317–30.
    • 2.
      Kathlean P, Eric W, Cole M. and James F. Simple random sampling. Advanced sampling theory with applications. Dordrecht: Springer Netherlands; 2003. pp. 71–136.
    • 3.

      Three calibration techniques combined with sample-effective design of experiment based on Latin hypercube sampling for direct detection of lanthanides in REE-rich ores using TXRF and WDXRF

      Akhmetzhanov, T; Pashkova, G; Chubarov, V; Labutin, T; Popov, A. J. Anal. Atom. Spectrom Vol. 36, .
    • 4.

      Greenness, whiteness and blueness assessment of high-performance liquid chromatographic methods for determination of cannabinoids in cosmetics

      N Sammut Bartolo; J Vella Szijj. Green Anal Chem Vol. 13, (2025).
    • 5.

      Evolution of green sample preparation: fostering a sustainable tomorrow in analytical sciences

      H Martínez-Pérez-Cejuela; E Gionfriddo. Anal Chem Vol. 96, (2024): 7840-63.
    • 6.

      Development of a novel quality by design–enabled stability-indicating HPLC method and its validation for the quantification of nirmatrelvir in bulk and pharmaceutical dosage forms

      P Alegete; S Byreddy. Biomed Chromatogr Vol. 38, (2024): 5812-20.
    • 7.

      Sustainable and technically smart spectrophotometric determination of PAXLOVID: a comprehensive ecological and analytical performance rating

      SI Aboras; HM Maher; NZ Alzoman; HS Elbordiny. BMC Chem Vol. 18, (2024): 184-200.
    • 8.

      Uncertainty and Latin hypercube sampling in geotechnical earthquake engineering

      A Karatzetzou. Geotechnics Vol. 4, (2024): 1007-25.
    • 9.

      Simultaneous measurement of COVID-19 treatment drugs (nirmatrelvir and ritonavir) in rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study

      Zhou, Chen-Jian; Liu, Ya-Nan; Wang, An-zhou; Wu, Hua-lu; Xu, Ren-Ai; Zhang, Qiang. Heliyon; Elsevier Vol. 10, Iss. 11, (2024).
    • 10.

      A simple and rapid LC-MS/MS method for the quantification of nirmatrelvir/ritonavir in plasma of patients with COVID-19

      X Zhu; L Li; B Dai; Z Liu; Z Wang; L Cui. Int J Anal Chem Vol. 2024, (2024).
    • 11.

      Hyphenating sustainability with chemometrics in chromatographic analysis of COVID combo therapy, nirmatrelvir and Molnupiravir, in presence of their overlapping degradation products; blue-green dual evaluation tools

      SI Aboras. J Chromatogr B Vol. 1247, (2024).
    • 12.

      A validated LC-MS/MS method for determination of six Anti-SARS-CoV-2 drugs in plasma and its application for a Pharmacokinetic study in rats

      Z Xu; C Li; X Qian; H Duan; J Zhou; Q Zhang. J Chromatogr B Vol. 1235, (2024).
    • 13.

      Simultaneous quantification of nirmatrelvir/ritonavir in human serum by LC–HRMS

      F Zhao; Z Xiang; J Han; J Pan; Y Qu; K Fan. J Pharm Biomed Anal Vol. 237, (2024).
    • 14.

      Novel stability indicating HPLC method for the quantification of nirmatrelvir in bulk drugs

      P Ilayaraja; M Manivannan; P Parthiban. Microchem J Vol. 196, (2024).
    • 15.

      A green method for the preparation of carbon quantum dots from yellow lupin peel waste for spectrofluorometric determination of nirmatrelvir

      T Alomar; N AlMasoud; FR Mansour. Spectrochim Acta Part A Mol Biomol Spectrosc Vol. 322, (2024).
    • 16.

      Sustainable chemometric analysis of tension headache drugs in the presence of nephrotoxic impurities

      SS Soliman; MA Abdel Rahman. Sustain Chem Pharm Vol. 42, (2024).
    • 17.

      Green adherent degradation kinetics study of nirmatrelvir, an oral anti-COVID-19: characterization of degradation products using LC–MS with insilico toxicity profile

      SI Aboras; HM Maher. BMC Chem Vol. 17, (2023): 1-14.
    • 18.

      Higher sensitive selective spectrofluorometric determination of Ritonavir in the presence of nirmatrelvir: application to new FDA approved co-packaged COVID-19 pharmaceutical dosage and spiked human plasma

      MS Imam; AH Abdelazim; S Ramzy; AA Almrasy; M Gamal; AS Batubara. BMC Chem Vol. 17, (2023).
    • 19.

      Homogeneous liquid–liquid Microextraction coupled with HPLC/DAD for determination of nirmatrelvir and Ritonavir as COVID-19 combination therapy in human plasma

      IA Abdallah; SF Hammad; A Bedair; FR Mansour. BMC Chem Vol. 17, (2023): 1-11.