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ABSTRACT:
The chemistry of metal complexes with tailor made Schiffbase ligands and their applications have aroused considerable interest because of preparative accessibility, diverse reactivity and structural variability. A novel Schiffbase ligand OHAPPTH (p-Toulic Hydrazide and o-Hydroxy acetophenone Schiffbase) and its Mn (II), Co (II), Ni (II) and Cu (II) metal complexes have been synthesized and characterized by various physio chemical methods viz. FT-IR, H1-NMR, UV-Visible, ESR, VSM, Molar conductance, XRD and micro analytical data and found to be anti bacterial activity. The magnetic properties of these Mn (II), Co (II), Ni (II) and Cu (II) complexes are 5.25 B.M. 4.80 B.M., 3.06 B.M and 1.68 B.M respectively. This result clearly indicates that the metal complexes of this ligand show octahedral geometry. The IR spectrums of these Schiffbase metal complexes shows bands at 1603cm-1, 1588cm-1 1612cm-1 and 1598cm-1 respectively, which is assigned to (C=N) stretching vibrations, a fundamental feature of azomethine group. The structural assessment of these complexes has been carried out based on above physio-chemical and spectroscopic methods. These Schiffbase and its metal complexes show a good activity against E. coli and Basillus subtiles. The anti bacterial results also indicate that the metal complexes are better antibacterial agents as compare to the Schiffbase.
KEYWORDS: Schiffbase, anti bacterial activity, characterization, Copper (II), Nickel (II), Cobalt (II), Manganese (II), OHAPPTH.
1. INTRODUCTION:
The preparation of a new ligands was a perhaps the most important step in the development of metal complexes which exhibit unique properties and novel reactivity. Schiffbase were important class of ligands, such ligands and their complexes had a variety of applications including biological, clinical, analytical and industrial in addition to their important roles in catalysis and organic synthesis.1 Schiffbase ligands have an affinity for transition metals such as Cu, Mn, Co and Fe. Maihub et al.3 (2005) prepared and investigated some Schiffbase complexes of Co (II), Ni (II) and Cu (II) ions. It is found that prepared complexes have square planar structures. The Ben Saber et al.2 (2005) reported the synthesis and characterizations of Cr (III), Fe (II), Co (II) and Ni (II) complexes with a Schiffbase derived from 4-dimethyl amino benzaldehyde and primary amines. The chemical analysis data showed the formation of (1:1) metal ligand ratio and a squre planar geometry...