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Emerging opportunistic yeast infections
Miceli MH, Diaz JA, Lee SA.
Loncef Infect Dis 2011;1 1:142-51.
Although Candida albicans is the most common cause of invasive yeast infection in the hospital setting, the growing number of new infections from non-albicans Candida spp. is increasingly being recognized. These authors summarize the changing epidemiology of uncommon invasive yeast infection. Early and specific diagnosis is crucial, and the decision to treat a patient with uncommon infection is often based on limited clinical and microbiological information. The authors state that although rare invasive yeast infections are uncommon, treatment decisions need careful consideration of the epidemiological factors combined with the immunological factors of the patients at risk.
Candida albicans is the predominant cause of invasive fungal infection (IFI) from yeast. Nevertheless, the epidemiology of invasive yeast infection is rapidly evolving and nonalbicans Candida spp. and other yeasts have emerged as major opportunistic pathogens [I]; however, geographical and institutional differences are widely reported. The current authors discuss the changing epidemiology of uncommon yeast infections.
Candida spp. become pathogens when the host's resistance to infection is impaired systemically or locally....