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About the Authors:
Thomas W. Geisbert
Affiliations National Emerging Infectious Diseases Laboratories Institute, Boston University School of Medicine, Boston, Massachusetts, United States of America, Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America
Kathleen M. Daddario-DiCaprio
Affiliation: National Emerging Infectious Diseases Laboratories Institute, Boston University School of Medicine, Boston, Massachusetts, United States of America
Andrew C. Hickey
Affiliation: Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America
Mark A. Smith
Affiliations Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America, Pathology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, United States of America
Yee-Peng Chan
Affiliation: Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America
Lin-Fa Wang
Affiliation: Australian Animal Health Laboratory, Livestock Industries, Australian Commonwealth Scientific and Research Organization, Geelong, Victoria, Australia
Joseph J. Mattapallil
Affiliation: Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America
Joan B. Geisbert
Affiliation: National Emerging Infectious Diseases Laboratories Institute, Boston University School of Medicine, Boston, Massachusetts, United States of America
Katharine N. Bossart
Affiliations National Emerging Infectious Diseases Laboratories Institute, Boston University School of Medicine, Boston, Massachusetts, United States of America, Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
Christopher C. Broder
* E-mail: [email protected]
Affiliation: Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America
Introduction
Nipah virus (NiV) is a recently recognized viral zoonotic pathogen of the family Paramyxoviridae that is distinguished by its ability to cause fatal disease in both animal and human hosts. NiV along with Hendra virus (HeV) comprise the new genus Henipavirus (reviewed [1], [2]). NiV was first identified during an outbreak of severe encephalitis in Malaysia and Singapore in 1998–99 that involved hundreds of people and more than 100 deaths, with pigs serving as the intermediate amplifying host [3], [4]. Since 1998 there have been more than a dozen recognized occurrences of human NiV infection, primarily in Bangladesh and India (reviewed [5]) with the two most recent outbreaks in March 2008 [6] and January 2010...