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About the Authors:
Chunyu Zhang
Current address: COPD program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America
Affiliation: Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Abdel G. Elkahloun
Affiliation: Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Matthew Robertson
Affiliation: Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Joell J. Gills
Affiliation: Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Junji Tsurutani
Affiliations Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America, Medical Oncology Department, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan
Joanna H. Shih
Affiliation: Biometric Research Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Junya Fukuoka
Affiliations Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Surgical Pathology, Toyama University Hospital, Toyama, Japan
M. Christine Hollander
Affiliation: Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Curtis C. Harris
Affiliation: Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
William D. Travis
Affiliation: Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America
Jin Jen
Affiliations Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
Phillip A. Dennis
* E-mail: [email protected]
Affiliation: Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Introduction
Lung cancer is the leading cause of cancer death throughout the world, causing approximately 1.2 million deaths annually and an estimated 157,300 deaths in the US in 2010 [1]. NSCLC most commonly occurs in smokers [2]. In the US, approximately 90% of deaths from lung cancer in men and 79% in...