Abstract
Head computed tomography (CT) scan showed bilateral caudate atrophy [Figure 1]a. Magnetic resonance imaging (MRI) brain showed bilaterally symmetrical hypo-intensities in globus pallidus, substantia nigra, and red nucleus on T2- and susceptibility-weighted images along with caudate and posterior putaminal atrophy [Figure 1]b-d. MRI of the brain in PKAN shows the classic 'eye-of-the-tiger' appearance, attributed to iron deposition in the globus pallidus, which causes a proton relaxation effect, resulting in a decrease in T1 and T2 relaxation times and decreased signal intensity in the globus pallidus, while the central hyper-intensity is attributed to intense gliosis.
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