Abstract

Doc number: 72

Abstract: ParaHox genes, and their evolutionary sisters the Hox genes, are integral to patterning the anterior-posterior axis of most animals. Like the Hox genes, ParaHox genes can be clustered and exhibit the phenomenon of colinearity - gene order within the cluster matching gene activation. Two new instances of ParaHox clustering provide the first examples of intact clusters outside chordates, with gene expression lending weight to the argument that temporal colinearity is the key to understanding clustering.

See research articles: http://www.biomedcentral.com/1741-7007/11/68 and http://www.biomedcentral.com/1471-2148/13/129

Details

Title
Time is of the essence for ParaHox homeobox gene clustering
Author
Garstang, Myles; Ferrier, David EK
Pages
72
Publication year
2013
Publication date
2013
Publisher
BioMed Central
e-ISSN
17417007
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/1741-7007-11-72
ProQuest document ID
1373275228
Copyright
© 2013 Garstang and Ferrier; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.