Paracetamo

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1. What percentage of poison-related admissions to hospital is associated with paracetamol overdose?

a) 20 *

b) 40 *

c) 60 *

d) 80 *

2. The maximum daily dose of paracetamol for an adult is:

a) 2g *

b) 3g *

c) 4g *

d) 5g *

3. Paracetamol:

a) Is an analgesic *

b) Is an antipyretic *

c) Inhibits prostaglandin synthesis *

d) All of the above *

4. Oxidation of paracetamol by hepatic cytochrome P450 enzymes forms:

a) N-acetyl-p-benzoquinoneimine *

b) Mercapturate *

c) Cysteine conjugates *

d) Glutathione *

5. Following paracetamol overdose, peak plasma concentration is generally achieved within:

a) 5 minutes *

b) 30 minutes *

c) 2 hours *

d)...