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Two patients with dementia with lewy bodies experienced behavioural worsening while receiving modafinil.
A 79-year-old man with Alzheimer's disease was placed on modafinil 100 mg/day [route not stated] hypersomnolence. Two days later, he experienced a worsening of hallucinations, and the modafinil dosage was reduced to 50mg. His psychotic symptoms gradually decreased over the next week. At age 80 years, he was diagnosed with dementia with lewy bodies....
