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The present investigation, is based on psychoanalytic Clinic, through the study of two cases of three patients diagnosed with TRI receiving hemodyalisis treatment, having into account the increase of the cases and the characteristics of its presentation it is now considered a public health problem. The main aim is to describe the dynamic characteristics of the process of mourning in patients with TRI in renal therapy center of the city of Cartagena (Colombia). The methodology used for this research was through a qualitative type design. This research was developed with a clinical design through case studies, based on psychoanalytic hermeneutics, all this backed in the clinical history, the semi-structured individual and familiar interviews, The projective test of the drawing of the human figure Machover and TPT of Murray, analyzing their integration. We conclude the dominance of failed functions of parents, and that they are individuals from psychosomatic families, that use their illness to obtain secondary profits. [PUBLICATION ABSTRACT]