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Radiat Environ Biophys (2014) 53:469477 DOI 10.1007/s00411-014-0517-x
SHORT COMMUNICATION
Risks of circulatory diseases among Mayak PA workerswith radiation doses estimated using the improved Mayak Worker Dosimetry System 2008
Maria B. Moseeva Tamara V. Azizova
Evgenia S. Grigoryeva Richard Haylock
Received: 5 August 2013 / Accepted: 18 January 2014 / Published online: 31 January 2014 Springer-Verlag Berlin Heidelberg 2014
Abstract The new Mayak Worker Dosimetry System 2008 (MWDS-2008) was published in 2013 and supersedes the Doses-2005 dosimetry system for Mayak Production Association (PA) workers. It provides revised external and internal dose estimates based on the updated occupational history data. Using MWDS-2008, a cohort of 18,856 workers rst employed at one of the main Mayak PA plants during 19481972 and followed up to 2005 was identied. Incidence and mortality risks from ischemic heart disease (IHD) (International Classication of Diseases (ICD)-9 codes 410414) and from cerebrovascular diseases (CVD) (ICD-9 codes 430438) were examined in this cohort and compared with previously published risk estimates in the same cohort based on the Doses-2005 dosimetry system. Signicant associations were observed between doses from external gamma-rays and IHD and CVD incidence and also between internal doses from alpha-radiation and IHD mortality and CVD incidence. The estimates of excess relative risk (ERR)/Gy were consistent with those estimates from the previous studies based on Doses-2005 system apart from the relationship between CVD incidence and internal liver dose where the ERR/Gy based on MWDS-2008 was just over three times higher than the corresponding estimate based on Doses-2005 system.
Adjustment for smoking status did not show any effect on the estimates of risk from internal alpha-particle exposure.
Keywords Ischemic heart disease Cerebrovascular
diseases External gamma-ray exposure Internal
alpha-particle exposure Workers Mayak PA Smoking
Introduction
In recent years, effects of ionizing radiation on cardiovascular diseases have been studied in many cohorts (e.g., Grosche et al. 2011; Ivanov et al. 2006; Krestinina et al. 2013; Kreuzer et al. 2012; McGeoghegan et al. 2008; Muirhead et al. 2009; Preston et al. 2003; Vrijheid et al. 2007; Shimizu et al. 2010; Yamada et al. 2004). The current work continues a series of papers on non-cancer effects, in particular circulatory diseases, among Mayak Production Association (PA) workers occupationally exposed to external gamma-rays and/or internally to alpha-particles from incorporated alpha-emitting radioisotopes. The...