Content area
Abstract
A two-step sequential biocatalytic process for the synthesis of chiral hydroxyesters that combines a lipase-catalyzed decarboxylative aldol reaction followed by kinetic resolution has been developed. The excellent combination of conventional and unconventional functions provides an attractive route for expanding the applications of biocatalysis.[PUBLICATION ABSTRACT]
Details
Title
Biocatalytic Synthesis of Optically Active Hydroxyesters via Lipase-Catalyzed Decarboxylative Aldol Reaction and Kinetic Resolution
Author
Zhang, Wei-wei; Wang, Na; Feng, Xing-wen; Zhang, Yang; Yu, Xiao-qi
Pages
535-43
Publication year
2014
Publication date
May 2014
ISSN
02732289
e-ISSN
15590291
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1520289513
Copyright
Springer Science+Business Media New York 2014