Abstract

Calophyllum brasiliense is a rich source of bioactive coumarins, xanthones and biflavonoids. The aim of the study was to compare the phenol contents and the antioxidant activity of C. brasiliense extracts obtained by conventional and supercritical fluid extraction (SFE) methods, as well as the quantification of crude extracts and (-)-mammea A/BB yields. Dichloromethane and hexane were used as solvents for the conventional extractions and SFE was developed using supercritical CO2; the kinetic curves were modeled using a second-order empirical model. The dichloromethane extract presented the best total yield, although it showed the lowest content of (-)-mammea A/BB. The concentration of the coumarin was considerably higher in extracts obtained by the supercritical fluid method and a higher antioxidant activity was assigned to extracts obtained by this technique. Concerning the total phenolic contents, both the dichloro-methane and the supercritical extractions produced satisfactory amounts. The SFE method proved to be more promising than conventional methods.

Details

Title
Comparing Conventional and Supercritical Extraction of (-)-Mammea A/BB and the Antioxidant Activity of Calophyllum brasiliense Extracts
Author
Gonçalves, Renata Menoci; Lemos, Caroline Ortega Terra; Leal, Ivana Correa Ramos; Nakamura, Celso Vataru; Cortez, Diógenes Aparício Garcia; Silva, Edson Antonio da; Cabral, Vladimir Ferreira; Cardozo-Filho, Lúcio
Pages
6215-6229
Publication year
2013
Publication date
2013
Publisher
MDPI AG
e-ISSN
14203049
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1532129165
Copyright
Copyright MDPI AG 2013