Content area
Abstract
Highlights
* A bivalent vaccine candidate was generated using reverse genetics techniques. * A recombinant NDV vector expressing the aMPV-C G protein was constructed. * The replication of the recombinant virus was maintainedin vitro, yet attenuatedin vivo. * Immunoresponses against aMPV-C and NDV were induced in vaccinated turkeys. * Complete protection against NDV and partial protection against aMPV-C was conferred.
Details
Title
Generation and evaluation of a recombinant Newcastle disease virus expressing the glycoprotein (G) of avian metapneumovirus subgroup C as a bivalent vaccine in turkeys
Author
Hu, Haixia; Roth, Jason P; Estevez, Carlos N; Zsak, Laszlo; Liu, Bo; Yu, Qingzhong
Pages
8624-8633
Publication year
2011
Publication date
Nov 3, 2011
ISSN
0264410X
e-ISSN
18732518
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1551973422
Copyright
Copyright Elsevier Limited Nov 3, 2011