Abstract

Pachydermoperiostosis or primary hypertropic osteoarthropathy is a rare hereditary disorder that was first described in 1868. It is characterized by digital clubbing, pachydermia (thickening of the facial skin and/or scalp), and periostosis (swelling of periarticular tissue and subperiosteal new bone formation). We report a case of a patient with the complete form of the disease, and with a unique appearance of the hair shaft and eyelashes. The authors propose a possible mechanism to justify the abnormalities observed in the patient's hair shafts regarding the metabolism of prostaglandins and its relationship with the hair follicle physiological cycle.

Details

Title
The action of prostaglandins on ciliary hypertrichosis: A case report of pachydermoperiostosis
Author
Zarur, Fabiana; d'Almeida, Luiza; Novellino, Anna Beatriz; Reis, Maria Fernanda
Pages
25-26
Publication year
2014
Publication date
Jan-Mar 2014
Publisher
Medknow Publications & Media Pvt. Ltd.
ISSN
09747753
e-ISSN
09749241
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1552668953
Copyright
Copyright Medknow Publications & Media Pvt Ltd Jan-Mar 2014