Content area
Abstract
Peptide natural product backbones are typically made ribosomally or by NRPS machinery. Exploration of pheganomycin biosynthesis defines a third hybrid model in which a grasp ligase joins an NRPS product with a ribosomally produced peptide.
Details
Title
A peptide ligase and the ribosome cooperate to synthesize the peptide pheganomycin
Author
Noike, Motoyoshi; Matsui, Takashi; Ooya, Koichi; Sasaki, Ikuo; Ohtaki, Shouta; Hamano, Yoshimitsu; Maruyama, Chitose; Ishikawa, Jun; Satoh, Yasuharu; Ito, Hajime; Morita, Hiroyuki; Dairi, Tohru
Pages
71-76
Publication year
2015
Publication date
Jan 2015
ISSN
15524450
e-ISSN
15524469
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1647100228
Copyright
Copyright Nature Publishing Group Jan 2015