Content area
Full Text
Int Urol Nephrol (2015) 47:451455 DOI 10.1007/s11255-015-0911-6
UROLOGY - ORIGINAL PAPER
The possible role of percutaneous tibial nerve stimulation using adhesive skin surface electrodes in patients with neurogenic detrusor overactivity secondary to spinal cord injury
Guoqing Chen Limin Liao Yao Li
Abstract
Purpose To compare the effectiveness of percutaneous tibial nerve stimulation (PTNS) using adhesive skin surface electrodes versus solifenacin succinate (SS) in patients with neurogenic detrusor overactivity (NDO) secondary to spinal cord injury (SCI).
Methods A randomized controlled study involving 100 patients with NDO secondary to SCI was conducted. Patients were randomized into two groups. In group A, patients received PTNS using adhesive skin surface electrodes for 4 weeks. In group B, patients underwent SS treatment for 4 weeks. Bladder diaries and incontinence quality of life questionnaire were reviewed before treatment and 2 and 4 weeks after treatment.
Results Improvement in all bladder diary parameters was statistically signicant within each group 2 and 4 weeks after treatment compared to baseline (p < 0.05), but did not reach statistical signicance between the PTNS and SS groups (p > 0.05). Compared to SS, PTNS was not associated with any unanticipated adverse events.
Conclusions PTNS therapy with adhesive skin surface electrodes is an effective method to treat NDO secondary to SCI. This therapy is not only no difference comparing
G. Chen L. Liao (*)
Department of Urology, China Rehabilitation Research Center, Beijing 100068, Chinae-mail: [email protected]
G. Chen L. Liao
Department of Urology, Capital Medical University, Beijing, China
Y. Li
Neural Electro-Mechanics Center, Chongqing Institute of Green and Intelligent Technology (CIGIT), Chinese Academyof Science, Chongqing, China
Received: 1 November 2014 / Accepted: 9 January 2015 / Published online: 22 January 2015 Springer Science+Business Media Dordrecht 2015
to SS therapy but also noninvasive and easily managed by patients.
Keywords Neurogenic detrusor overactivity Spinal cord injury Percutaneous tibial nerve stimulation Solifenacin Succinate Surface electrodes
Introduction
Neurogenic bladder (NB) dysfunction after spinal cord injury (SCI) is a major medical and social problem. Prevention of upper urinary tract damage and renal failure is the ultimate goal of any urologic treatment, but urinary incontinence associated with neurogenic detrusor overactivity (NDO) can greatly reduce the quality of life [1].
Currently, clean intermittent catheterization (CIC) combined with an anticholinergic medication is the gold standard treatment...