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From a retrospective study, 7 patients [sexes not stated] aged 14-25 years were identified who developed dependency and epilepsy following abuse of tramadol while concomitantly consuming caffeine in the form of coffee.
All of the patients presented 1 day-3 months after developing seizures and were diagnosed with epilepsy. All of the patients were abusing tramadol 880-1200 mg/day [duration of...
