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Abstract [Objectivep] The paper was to study the insecticidal activity and field efficacy of cyhalodiamide, a novel insecticide developed by Zhejiang Research Institute of Chemical Industry, Ltd. [Method] Toxicity of cyhalodiamide against Plutella xylostella, Spodoptera exigua, Prodenia litura and Chilo suppressalis were tested in the laboratory by leaf-dipping method, and the field efficacy of cyhalodiamide against P. xylostella, S. exigua, P. litura, Pieris rapae, C. suppressalis and Cnaphalocrocis medinalis was evaluated. [Result] The LC^sub 50^ values of cyhalodiamide against P. xylostella, S. exigua, P. litura and C. suppressalis were 0.046, 0.072 , 0.071 and 1.95 mg/L, respectively, almost equivalent to that of flubendiamide and chlorantraniliprole. The control efficacy of 20% Z4042 SC (30 g/hm^sup 2^) against P. xylostella, S. exigua, P. litura and P. rapae was 90.1% - 96.3% after spraying for 7 d, and its control efficacy against C. suppressalis and C. medinalis was 82.9% -90.5% after spraying for 15 d. No crop injury was observed at the test dosage. [Conclusion] The study provided reference for field control against Lepidoptera pests.
Key words Insecticide; Cyhalodiamide; Lepidoptera pests; Insecticidal activity; Field efficacy
Phthalic diamides is a kind of new insecticides found in recent years with high efficacy, low toxicity and unique mechanism, which act on ryanodine receptor ( RyR ) of insects to promote the release of endogenous calcium ion of insect cells and to affect muscle contraction, thus leading to death of insects l-']. In recent years, this kind of insecticides has become a hot research topic in new pesticide development 1-3 . Cyhalodiamide j 3-chloro-A'-l - methyl-1 -cyano-ethyl-A'-[2-methy 1-4-( 1, 2, 2, 2-tetrafluoro-l-trifluoromethyl-ethyl ) -phenyl ]-phthalamide ] , an insecticidal phthalic diamides developed by Zhejiang Research Institute of Chemical Industry, Ltd. , has applied national invention patent 4] , and its chemical structure is shown in the following (I) formula.
Zhejiang Yangtze River Delta Chemical Safety Evaluation Co. , Ltd. has been commissioned to carry out toxicity test of cyhalodiamide in previous period, and the results show that the acute oral LD50 for rats (male, female) is > 5 000 mg /kg, and the acute dermal LD50 is > 2 000 mg /kg; there is no irritant to rabbit skin and eyes; Ames test, mice testis spermatocyte chromosome aberration test and...