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Annals of Biomedical Engineering, Vol. 43, No. 4, April 2015 ( 2014) pp. 844857 DOI: 10.1007/s10439-014-1191-5
Emerging Trends in Heart Valve Engineering: Part II. Novel and Standard Technologies for Aortic Valve Replacement
ARASH KHERADVAR,1,2 ELLIOTT M. GROVES,1,2 CRAIG J. GOERGEN,3 S. HAMED ALAVI,1
ROBERT TRANQUILLO,4 CRAIG A. SIMMONS,5,6 LAKSHMI P. DASI,7 K. JANE GRANDE-ALLEN,8
MOHAMMAD R. K. MOFRAD,9 AHMAD FALAHATPISHEH,1 BOYCE GRIFFITH,10,11 FRANK BAAIJENS,12
STEPHEN H. LITTLE,13 and SUNCICA CANIC14
1Department of Biomedical Engineering, The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, 2410 Engineering Hall, Irvine, CA 92697-2730, USA; 2Department of Internal Medicine, Division of Cardiology, University of California, Irvine School of Medicine, Irvine, CA, USA; 3Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA; 4Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA; 5Department of Mechanical & Industrial Engineering, University of Toronto, Toronto, ON, Canada; 6Institute of
Biomaterials & Biomedical Engineering, University of Toronto, Toronto, ON, Canada; 7Department of Mechanical Engineering, School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA; 8Department of Bioengineering, Rice University, Houston, TX, USA; 9Department of Bioengineering and Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA; 10Department of Mathematics, Center for Interdisciplinary Applied Mathematics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; 11McAllister Heart Institute, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA; 12Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands; 13Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA; and
14Department of Mathematics, University of Houston, Houston, TX, USA
(Received 21 July 2014; accepted 13 November 2014; published online 2 December 2014)
Associate Editor Estefana Pena oversaw the review of this article.
AbstractThe engineering of technologies for heart valve replacement (i.e., heart valve engineering) is an exciting and evolving eld. Since the rst valve replacement, technology has progressed by leaps and bounds. Innovations emerge frequently and supply patients and physicians with new, increasingly efcacious and less invasive treatment options. As much as any other eld in medicine the treatment of heart valve disease has experienced a renaissance in the last 10 years. Here we review the currently available technologies and future options in the surgical and transcatheter treatment of aortic valve disease. Different valves from major...