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Anal Bioanal Chem (2014) 406:22112215 DOI 10.1007/s00216-013-7379-y
NOTE
Silica supported Fe3O4 magnetic nanoparticles for magnetic solid-phase extraction and magnetic in-tube solid-phase microextraction: application to organophosphorous compounds
Y. Moliner-Martinez & Yosmery Vitta &
Helena Prima-Garcia & R. A. Gonzlez-Fuenzalida &
Antonio Ribera & P. Campns-Falc & Eugenio Coronado
Received: 10 June 2013 /Revised: 27 August 2013 /Accepted: 16 September 2013 /Published online: 9 October 2013 # Springer-Verlag Berlin Heidelberg 2013
Abstract This work demonstrates the application of silica supported Fe3O4 nanoparticles as sorbent phase for magnetic solid-phase extraction (MSPE) and magnetic on-line in-tube solid-phase microextraction (Magnetic-IT-SPME) combined with capillary liquid chromatographydiode array detection (CapLC-DAD) to determine organophosphorous compounds (OPs) at trace level. In MSPE, magnetism is used as separation tool while in Magnetic-IT-SPME, the application of an external magnetic field gave rise to a significant improvement of the adsorption of OPs on the sorbent phase. Extraction efficiency, analysis time, reproducibility and sensitivity have been compared. This work showed that Magnetic-IT-SPME can be extended to OPs with successful results in terms of simplicity, speed, extraction efficiency and limit of detection. Finally,
wastewater samples were analysed to determine OPs at nano-grams per litre.
Keywords Magnetic nanoparticles . Organophosphorous pesticides . Magnetic solid-phase extraction and magnetic in-tube solid-phase microextraction
Introduction
Hybrid magnetic nanoparticles (NPs) have been widely used to develop new (micro)extraction techniques. In this context, most applications are based on their use for magnetic solid-phase extraction (MSPE) or dispersive (micro)solid-phase extraction (D-()SPE). These adsorbents exhibit superpara-magnetic behaviour that makes them especially attractive for MSPE because they can be concentrated and separated from solutions easily at low magnetic field gradients [1, 2]. These methods, however, require several sample pretreatment steps. In this respect, in-tube solid-phase microextraction (IT-SPME) can overcome this limitation as it facilitates sample processing, especially in hyphenated liquid chromatography (LC) techniques. Nevertheless, the main drawback of IT-SPME is the poor extraction capacity. Recently, we reported the use of silica supported Fe3O4 magnetic nanoparticles (MNPs) as sorbent phase for IT-SPME (Magnetic-IT-SPME) [3]. In this approach, a magnetic hybrid material was immobilized on the surface of a bared fused silica capillary column and utilized as injection loop providing quantitative extraction efficiencies for pharmaceutical emerging pollutants.
Herein, the objective of this work has been to study the adsorption of organophosphorous...