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Abstract :
The aim of this review is to know more about the anti - ulcer property of the medicinal plants.An ulcer is an erosion in the lining of the stomach and duodenum.There are two types of ulcers -gastric and duodenal ulcer.Together ,they are called peptic ulcer.There are many herbs and plant products that have been found to play a role in protecting or helping to heal stomach and peptic ulcers.In recent years,gastric ulcer has also been associated with infection of gastrointestinal mucosal tissue by Helicobacter pylori . Herbal plants are considered as safe for peptic ulcer treatment with less side effect.This article reviews the features of some of the plants like Ocimum sanctum L.,Morus alba L.,Musa acuminata, Mangifera indica L., Zingiber officinalis Roscoe are reported to possess antiulcer and ulcer healing properties.
Keywords:Erosion,helicobacter pylori,duodenum,gastrointestinal mucosal tissue.
INTRODUCTION :
Peptic ulcer is a gastro intestinal disorder due to an imbalance between the aggressive factors like acid, pepsin, Helicobacter pylori and defensive factors like bicarbonate secretion, prostaglandins, gastric mucus, innate resistance of the mucosal cell factors (1).Normally peptic ulcer develops when aggressive factors overcome the defensive factors (2).Peptic ulcer can be categorized on the basis of location and on the severity of disease.Basically, word "peptic" is derived from Greek term "peptikos" whose meaning is related to digestion .Various reports indicates that old age group patients are more prone to gastric ulcer. Younger individuals have higher risk of duodenal ulcers .A number of drugs including proton pump inhibitors and H2 receptor antagonists are available for the treatment of peptic ulcer, but clinical evaluation of these drugs has shown incidence of relapses, side effects, and drug interactions. But therapeutic uses of plant are safe, economical & effective as their ease of availability(3) .Different plants are rich source of medicines.Currently, increasing health concern urged the researchers to revitalize the natural products and to alleviate the diseases without harming the body. This study has presented the review of commonly used anti-ulcer plants which are used for the treatment or prevention of peptic ulcers. Plants such as Ocimum sanctum L.,Morus alba L.,Musa acuminata, Mangifera indica L., Zingiber officinalis Roscoe are reviewed here.
Ocimum sanctum Linn
Ocimum sanctum belong to family Lamiaceae are very important for their therapeutic potential. Ocimum...