Comment
Open Access
Cressey D. UK funders demand strong statistics for animal studies. Nature. 2015;520:271-2.
Experimental Design Assistant. https://www.nc3rs.org.uk/experimental-design-assistant-eda.
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Copyright BioMed Central 2015
Abstract
Virus B is a newly emerged viral strain for which there is no current treatment. Drug A was identified as a potential treatment for infection with virus B. In this pre-clinical phase of drug testing, the effects of drug A on survival after infection with virus B was tested. There was no difference in survival between control (dark blue) and drug A-treated, virus B-infected mice (green), but a significant difference in survival between control and virus B-infected mice without drug treatment (light blue, z-test for proportions P < 0.05, n = 30 in each group). The authors therefore concluded that drug A is effective in reducing mouse mortality due to virus B.
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