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The human papillomavirus (HPV) can infect the skin and mucous membranes. Common warts, filiform warts, epidermodysplasia verruciformis, mosaic warts and plantar warts represent clinical manifestations of infection with HPV. Giant warts in the hands are very rare in immunocompetent adults and sometimes by their extension or atypical location represent a diagnostic and therapeutic challenge. The giant tumours caused by HPV are more common in the anogenital region where they are known as Buschke-Loewenstein tumours. No risk factor has yet been identified for giant warts in immunocompetent patients.
The authors report...