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The FDA approved everolimus to treat adults with progressive, well-differentiated, nonfunctional neuroendocrine tumors of gastrointestinal or lung origin that are unresectable, locally advanced or metastatic.
The FDA based its decision in part on results from the RADIANT-4 trial, a multicenter, randomized, placebo-controlled trial of 302 patients who experienced disease progression within 6 months of randomization.
Researchers randomly assigned patients 2:1 to receive...