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A 26-year-old woman developed various toxicities following lamotrigine overdose in a suicide attempt.
The woman, who had a history of bipolar mood disorder, was admitted to the hospital, 40 minutes after a suicide attempt by ingesting 200 tablets of 200mg lamotrigine. Her serum evaluation revealed high levels of lamotrigine without any other aetiology for mental dysfunction. She was noted as weak, agitated, drowsy, lethargic, tachycardic, dehydrated, with blurred vision, diplopia, headache, dizziness and sweating. She also complained of abdominal pain. Though nothing was seen in the examination, bowel sounds were observed. Within 20 minutes of admission, she vomited and underwent a generalised tonic-clonic seizure that lasted for 2 minutes. Then she lost her consciousness and her Glasgow coma score (GCS) dipped from 12/15 to 6-7/15. She was not opening her eyes, but was responding to pain. Subsequently, she...