Abstract
Background
The purpose of this study was twofold: to evaluate the quantitative stability of a SPECT/CT gamma camera over time and to determine if daily flood acquisitions can reliably serve as calibration factors for quantitative SPECT. Using a cylindrical water phantom filled with measured amounts of 99mTc, factors were calculated to convert counts/cc to activity/cps. Measurements were made over an 18-month period. System sensitivity data calculated from 57Co daily quality assurance (DQA) flood acquisitions were then compared to the 99mTc calibration factors to determine the relationship of the factors.
Results
The coefficient of variation is 2.7 % for the 99mTc cylinder conversion factors and 2.6 % for the 57Co DQA flood data. The greatest difference between the cylinder conversion factors and the flood data is less than 3 %.
Conclusions
Based on the results, the camera was stable within 3 % over an 18-month time period. The daily flood source acquisitions can be a reliable source for tracking camera stability and may provide information on updating the calibration factor for quantitative imaging.
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