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Web End = Int J Cardiovasc Imaging (2017) 33:577584 DOI 10.1007/s10554-016-1024-8
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http://crossmark.crossref.org/dialog/?doi=10.1007/s10554-016-1024-8&domain=pdf
Web End = Assessment ofmyocardial delayed enhancement withcardiac computed tomography incardiomyopathies: aprospective comparison withdelayed enhancement cardiac magnetic resonance imaging
Abstract To evaluate the feasibility of cardiac CT for the evaluation of myocardial delayed enhancement (MDE) in the assessment of patients with cardiomyopathy, compared to cardiac MRI. A total of 37 patients (mean age 54.9 15.7 years, 24 men) who underwent cardiac MRI to evaluate cardiomyopathy were enrolled. Dual-energy ECG-gated cardiac CT was acquired 12min after contrast injection. Two observers evaluated cardiac MRI and cardiac CT at dierent kV settings (100, 120 and 140 kV) independently for MDE pattern-classication (patchy, transmural, subendocardial, epicardial and mesocardial), dierentiation between ischemic and non-ischemic cardiomyopathy and MDE quantication (percentage MDE). Kappa statics and the intraclass correlation coefficient were used for statistical analysis. Among dierent kV settings, 100-kV CT showed excellent agreements compared to cardiac MRI for MDE detection ( = 0.886 and 0.873, respectively), MDE pattern-classication ( = 0.888 and 0.881, respectively) and dierentiation between ischemic and non-ischemic cardiomyopathy ( = 1.000 and 0.893, respectively) for both Observer 1 and Observer 2. The BlandAltman plot between MRI and 100-kV CT for the percentage MDE showed a very small bias (0.15%) with 95% limits of agreement of 7.02 and 6.72. Cardiac CT using 100 kV might be an alternative method to cardiac MRI in the
* Byoung Wook Choi [email protected]
1 Department ofRadiology, Research Institute ofRadiological Science, Severance Hospital, Yonsei University College ofMedicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul120-752, SouthKorea
2 Division ofCardiology, Cardiovascular Hospital, Severance Hospital, Yonsei University College ofMedicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul120-752, SouthKorea
HyeJeongLee1 DongJinIm1 JongChanYoun2 SuyonChang1 YoungJooSuh1 YooJinHong1 YoungJinKim1 JinHur1 ByoungWookChoi1
Received: 4 July 2016 / Accepted: 14 November 2016 / Published online: 22 November 2016 Springer Science+Business Media Dordrecht 2016
assessment of cardiomyopathy, particularly in patients with contraindications to cardiac MRI.
Keywords Cardiomyopathy Myocardial delayed enhancement Myocardial brosis Cardiac computed tomography Cardiac magnetic resonance imaging
Introduction
For cardiomyopathy, determining the exact etiology for each patient is important because etiology is directly related to treatment and patient survival [1]. In that sense, cardiac magnetic resonance imaging (MRI) with myocardial delayed enhancement (MDE) imaging using extracellular contrast agents has been well established for cardiomyopathy assessment...