Content area
Abstract
[...]the sketch is a map to direct peer scrutiny as a means to improve the precision of the model, to design future models and to collect future data sets. To capture the richness of specific knowledge, there are a number of domain-specific ontologies (https://bioportal.bioontology.org/ and https://www.ebi. ac.uk/ols/index), which in this example would explain how the sample was taken, what technology performed the assay, the units of the dependent variable and that the assay was to measure levels of the metabolite D-glucose. Many of the data sets with the highest reuse value fall into a small number of experimental designs: variant calls from genome sequencing or genotyping, somatic single-nucleotide variant calls for paired tumornormal samples in a cancer study, RNA sequencing, quantitative trait association or linkage mapping, genome-wide association with a SNP panel and population sequence variants displayed on a phylogenetic tree.





