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Abstract
Case Report A 31-year-old G1P1 woman presented to the Department of Obstetrics and Gynecology in Peking Union Medical College Hospital due to seizure at a gestational age of 36+4 weeks. Intermittent seizure was present 2 years after the delivery. [...]surgical treatment was recommended by the neurosurgical physicians, but the patient did not receive the surgery due to thyroid cancer 1 year after delivery. The incidence of intracranial hemorrhage was increased together with increase of cerebral angioma size in the pregnancy, which may be associated with the following aspects: the elevation of estrogen and progestogen resulted in high expression of growth factors (e.g., vascular endothelial growth factor and placenta growth factor), as well as change of blood pressure and proliferation of endothelial cells. No Cochrane evidence revealed the fact that cesarean delivery was related with reduced incidence of intracranial hemorrhage. [2] However, the incidence of hemorrhage in pregnancy with CCM was higher after receiving cesarean delivery or painless delivery at a gestational age of 32+ weeks (fetal weight >2 kg). [...]there is no increased risk of cranial hemorrhage associated with mode of delivery in the pregnancy with CCM. Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical...