Performance Characteristics of Hemolysis Index on Roche Cobas 8000 Automated Analyzers Including Correlation of Hemolysis Index With Free Hemoglobin Concentration in Plasma

Hemolysis is a common specimen abnormality that can interfere with many laboratory tests and lead to erroneous results and interpretations and to inappropriate medical decisions. Determination of the hemolysis index (HI), a dimensionless measure, is one method to assess for this interference. Our goals in this study were to: 1) validate our HI measurements as we transition to new core laboratory automated chemistry instruments (previous, Roche Modular [Roche Diagnostics, Indianapolis, IN]; new, Roche Cobas 8000); 2) determine...