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About the Authors:
Tegegn G. Jaleta
Contributed equally to this work with: Tegegn G. Jaleta, Siyu Zhou
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing - original draft
Affiliations Department of Evolutionary Biology, Max-Planck-Institute for Developmental Biology, Tübingen, Germany, Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Siyu Zhou
Contributed equally to this work with: Tegegn G. Jaleta, Siyu Zhou
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing - original draft
Affiliation: Department of Evolutionary Biology, Max-Planck-Institute for Developmental Biology, Tübingen, Germany
Felix M. Bemm
Roles Data curation, Formal analysis, Methodology, Software, Writing - original draft
Affiliation: Department of Molecular Biology, Max-Planck-Institute for Developmental Biology, Tübingen, Germany
Fabian Schär
Roles Conceptualization, Investigation, Methodology
Affiliations Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland
Virak Khieu
Roles Investigation, Methodology, Resources
Affiliation: National Center for Parasitology, Entomology and Malaria Control, Ministry of Health, Phnom Penh, Cambodia
Sinuon Muth
Roles Funding acquisition, Project administration, Resources
Affiliation: National Center for Parasitology, Entomology and Malaria Control, Ministry of Health, Phnom Penh, Cambodia
Peter Odermatt
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision
Affiliations Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland
James B. Lok
Roles Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing - review & editing
Affiliation: Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Adrian Streit
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing - original draft
* E-mail: [email protected]
Affiliation: Department of Evolutionary Biology, Max-Planck-Institute for Developmental Biology, Tübingen, Germany
ORCID http://orcid.org/0000-0002-7838-621XAbstract
Strongyloidiasis is a much-neglected soil born helminthiasis caused by the nematode Strongyloides stercoralis. Human derived S. stercoralis can be maintained in dogs in the laboratory and this parasite has been reported to also occur in dogs in the wild. Some authors have considered strongyloidiasis a zoonotic disease while others have argued that the two hosts carry host specialized populations of S. stercoralis and that dogs play a minor role, if any, as a reservoir for zoonotic S. stercoralis infections of humans. We isolated S. stercoralis from humans and their dogs in rural villages...