Transpulmonary thermodilution-derived haemodynamics in patients with liver failure: a prospective study in 351 patients

Abstract

[...]there is a lack of studies systematically investigating haemodynamics in patients with liver failure. [...]it was the aim of this study to compare transpulmonary thermodilution (TPTD)-derived haemodynamics of 112 patients with acute or chronic liver failure with 239 patients without liver failure. Despite comparable preload parameters, the following parameters were significantly different: patients with acute or chronic liver failure had significantly higher cardiac index (4.3 ± 1.3 vs. 3.3 ± 1.3 l/minute/ m2; P < 0.001), stroke volume index (50 ± 15 vs. 37 ± 15; P < 0.001), pulse pressure (75 ± 19 vs. 65 ± 21 mmHg; P = 0.021) and cardiac power index (0.7 ± 0.24 vs. 0.60 ± 0.28 W/m2; P < 0.001).