Content area
Abstract
This review commemorates the 40th anniversary of DNA sequencing, a period in which we have already witnessed multiple technological revolutions and a growth in scale from a few kilobases to the first human genome, and now to millions of human and a myriad of other genomes. DNA sequencing has been extensively and creatively repurposed, including as a 'counter' for a vast range of molecular phenomena. We predict that in the long view of history, the impact of DNA sequencing will be on a par with that of the microscope.
Details
Title
DNA sequencing at 40: past, present and future
Author
Shendure, Jay 1 ; Balasubramanian, Shankar 2 ; Church, George M 3 ; Gilbert, Walter 4 ; Rogers, Jane 5 ; Schloss, Jeffery A; Waterston, Robert H
1 Department of Genome Sciences, University of Washington, Seattle, Washington, USA
2 Department of Chemistry, University of Cambridge, Cambridge, UK
3 The Wyss Institute & Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
4 Department of Molecular and Cellular Biology, Harvard University, Cambridge Massachusetts, USA
5 International Wheat Genome Sequencing Consortium, Little Eversden, Cambridge, UK
1 Department of Genome Sciences, University of Washington, Seattle, Washington, USA
2 Department of Chemistry, University of Cambridge, Cambridge, UK
3 The Wyss Institute & Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
4 Department of Molecular and Cellular Biology, Harvard University, Cambridge Massachusetts, USA
5 International Wheat Genome Sequencing Consortium, Little Eversden, Cambridge, UK
Pages
1-9
Section
REVIEW
Publication year
2017
Publication date
Oct 19, 2017
ISSN
00280836
e-ISSN
14764687
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1954333717
Copyright
Copyright Nature Publishing Group Oct 19, 2017