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Most effective drugs for erectile dysfunction (ED), phosphodiesterase-5 inhibitors (PDEIs), target NO-cGMP pathway. So does novel Russian remedy Impaza; unlike PDEIs, it enhances NO-synthase activity and NO production in cavernous tissue. Efficacy and safety of impaza studied in 12-week randomized placebo-controlled trials covered 200 ED outpatients. Impaza was taken without strict attachment to sexual activity. Internation Index ofErectile Function (HEF) scores, patient's global assessment...