Abstract

Mobile phone microscopes are a natural platform for point-of-care imaging, but current solutions require an externally powered illumination source, thereby adding bulk and cost. We present a mobile phone microscope that uses the internal flash or sunlight as the illumination source, thereby reducing complexity whilst maintaining functionality and performance. The microscope is capable of both brightfield and darkfield imaging modes, enabling microscopic visualisation of samples ranging from plant to mammalian cells. We describe the microscope design principles, assembly process, and demonstrate its imaging capabilities through the visualisation of unlabelled cell nuclei to observing the motility of cattle sperm and zooplankton.

Details

Title
A dual-mode mobile phone microscope using the onboard camera flash and ambient light
Author
Orth, A 1 ; Wilson, E R 1   VIAFID ORCID Logo  ; Thompson, J G 2 ; Gibson, B C 1   VIAFID ORCID Logo 

1  ARC Centre of Excellence for Nanoscale BioPhotonics, School of Science, RMIT University, Melbourne, Australia 
2  ARC Centre of Excellence for Nanoscale BioPhotonics, Robinson Research Institute, School of Medicine, The University of Adelaide, Adelaide, Australia 
Pages
1-8
Publication year
2018
Publication date
Feb 2018
Publisher
Nature Publishing Group
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1038/s41598-018-21543-2
ProQuest document ID
2004099592
Copyright
© 2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.