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Abstract

A detailed chemical investigation of the secondary metabolites produced by the endophytic fungus Xylaria sp. isolated from the stems of Isodon sculponeatus afforded six new compounds, xylariahgins A–F (16), two new natural products (7 and 8), along with two known compounds (9 and 10) (Fig. 1). The structures of all compounds were unambiguously established by analyzing their spectroscopic data or referring to pertinent literature. Compounds 18 were tested for their cytotoxic activity against five human tumor cell lines.

Details

Title
Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
Author
Chen, Rong 1 ; Jian-Wei, Tang 2 ; Xing-Ren, Li 3 ; Liu, Miao 3 ; Wen-Ping, Ding 1 ; Yuan-Fei, Zhou 2 ; Wei-Guang, Wang 3 ; Du, Xue 3 ; Han-Dong, Sun 3 ; Pema-Tenzin Puno 3 

 School of Chemical Science and Technology, Yunnan University, Kunming, People’s Republic of China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People’s Republic of China 
 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People’s Republic of China; University of Chinese Academy of Sciences, Beijing, People’s Republic of China 
 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People’s Republic of China 
Pages
121-129
Publication year
2018
Publication date
Apr 2018
Publisher
Springer Nature B.V.
ISSN
21922195
e-ISSN
21922209
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2015462802
Copyright
Natural Products and Bioprospecting is a copyright of Springer, (2018). All Rights Reserved.