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Abstract. Panyawan extract (PE) was evaluated against goat's internal parasite for their anthelmintic effects. The aqueous stem extracts were chemically evaluated using modified and standard protocols and were found to contain tannins, saponins, flavonoids, alkaloids, steroids and phenols. The experiment was carried out in 5-cages with 10 goats in each treatment group and each goat served as a replicate using different concentrations of Albendazole-Benalvit, 1 mL PE/10 kg BW, 1.5 mL PE/10 kg BW, 2.5 mL PE/10 kg BW, 3.5 mL PE/10 kg BW. Distilled water was used as negative control. All freshly excreted feces were collected and placed in plastic cups and were immediately examined through Modified McMaster test to evaluate the anthelmintic activity of the designated treatments against parasitic gastrointestinal nematodes. Efficacies of different anthelmintics were examined at Regional Animal Disease Diagnostic Laboratory (RADDL), Brgy. Taguibo, Butuan City, Caraga-XIII. The evaluation criteria were based on the frequency counts of egg parasites (EPG) under the different treatments. Results were analyzed using the analysis of variance (ANOVA) of a Completely Randomized Design (CRD). Tukey's test or HSD was used to compare treatment means showing significant differences. The anthelmintic efficacy of the PE preparations was monitored through faecal egg count reduction (FECR), at regular intervals for a period of 10 and 14 days post-treatment in no-choice laboratory test. The highest reduction (EPG) of expelled egg parasite was 62.80 and 78.11% when PE was given at a dose of 3.5 mL/10 kgBW after 10 and 14 days of treatment, respectively. Although the FECR of goats treated with this dosage level was higher than those groups treated with 1.5 and 2.5 mL/10 kgBW of PE, the difference were not statistically significant. In the FECR of positive control, albendazole reduced the faecal egg count by 83.01% and 92.80% at 10 and 14 days respectively after treatment. PE had the highest number of nematode eggs expelled when given at 3.5 mL/10 kgBW and exposed within 10 and 14 days with 3,385 and 4,210 fecal egg count reduction (EPG), respectively.
Key Words: internal parasites, helminthiasis, panyawan extracts, plant secondary metabolites (PSM), fecal egg count.
Introduction. Panyawan (Tinospora rumphii Boerl.) is a vine found throughout the Philippines. It contains a bitter principle, colombine (2.22%), traces of alkaloids, and a glucoside. The...