Sporadic hemiplegic migraine and CREST syndrome

Abstract

Hemiplegic migraines are characterized by attacks of migraine with aura accompanied by transient motor weakness. There are both familial and sporadic subtypes, which are now recognized as separate entities by the International Classification of Headache Disorders, edition II (ICHD-II). The sporadic subtype has been associated with other medical conditions, particularly rheumatological diseases. We report the case of a woman with sporadic hemiplegic migraine associated with CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia). Since there is a close relationship between migraine and Raynaud's phenomenon, it could be speculated that the sporadic hemiplegic migraines in our patient might be secondary to CREST syndrome. [PUBLICATION ABSTRACT]