Content area

Abstract

Autism spectrum disorders (ASD) often go undetected in toddlers. The Modified Checklist for Autism in Toddlers (M-CHAT) was used to screen 3,793 children aged 16-30 months from low- and high-risk sources; screen positive cases were diagnostically evaluated. Re-screening was performed on 1,416 children aged 42-54 months. Time1 Positive Predictive Value (PPV) was .36 for the initial screening and .74 for the screening plus follow-up telephone interview; values were similar for Time2 PPV. When separating referral sources, PPV was low for the low-risk sample but acceptable with the follow-up telephone interview. Children with ASD from the low-risk and high-risk samples were highly similar. Results indicate that the M-CHAT continues to be a promising instrument for the early detection of ASD. [PUBLICATION ABSTRACT]

Details

Title
The Modified Checklist for Autism in Toddlers: A Follow-up Study Investigating the Early Detection of Autism Spectrum Disorders
Author
Kleinman, Jamie M; Robins, Diana L; Ventola, Pamela E; Pandey, Juhi; Boorstein, Hilary C; Esser, Emma L; Wilson, Leandra B; Rosenthal, Michael A; Sutera, Saasha; Verbalis, Alyssa D; Barton, Marianne; Hodgson, Sarah; Green, James; Dumont-mathieu, Thyde; Volkmar, Fred; Chawarska, Katarzyna; Klin, Ami; Fein, Deborah
Pages
827-39
Publication year
2008
Publication date
May 2008
Publisher
Springer Nature B.V.
ISSN
01623257
e-ISSN
15733432
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1007/s10803-007-0450-9
ProQuest document ID
205306980
Copyright
Springer Science+Business Media, LLC 2008