Depolymerized konjac glucomannan: preparation and application in health care

Abstract

Konjac glucomannan (KGM) is a water-soluble polysaccharide obtained from the roots and tubers of konjac plants. Recently, a degraded product of KGM, depolymerized KGM (DKGM), has attracted attention because of its low viscosity, improved hydrophily, and favorable physiological functions. In this review, we describe the preparation of DKGM and its prebiotic effects. Other health benefits of DKGM, covering antioxidant and immune activity, are also discussed, as well as its safety. DKGM could be a candidate for use as a tool for the treatment of various diseases, including intestinal flora imbalance, and oxidative- and immune-related disorders.

Alternate abstract:

概要

魔芋葡甘露聚糖是从魔芋块茎中提取的一种高分 子水溶性多糖。近些年研究表明,其解聚产物, 除了具有高溶解性和低粘度等良好的理化性质 外,还具有调节微生物菌群结构、抗氧化、免疫 调节等多种生理活性。本文重点综述了解聚型葡 甘露聚糖的制备方法以及菌群调节功能。除此之 外,对其抗氧化、免疫调节功能以及安全性评价 也进行了全面的总结,为解聚型葡甘露聚糖的研 究与应用提供一定的依据与思路。