MicroRNA expression profiling of goat peripheral blood mononuclear cells in response to peste des petits ruminants virus infection

Abstract

* Research article * Open Access MicroRNA expression profiling of goat peripheral blood mononuclear cells in response to peste des petits ruminants virus infection * Xuefeng Qi†1, * Ting Wang†1, * Qinghong Xue2, * Zhen Li1, * Bo Yang1 and * Jingyu Wang1Email author †Contributed equally Veterinary Research201849:62 https://doi.org/10.1186/s13567-018-0565-3 © The Author(s) 2018 Received: 1 February 2018 Accepted: 29 May 2018 Published: 16 July 2018 Abstract Peste des petits ruminants virus (PPRV) belongs to the genus Morbillivirus that causes an acute and highly contagious disease in goats and sheep. Here, we employed deep sequencing technology to determine cellular miRNA expression profile in goat peripheral blood mononuclear cells (PBMC) infected with Nigeria 75/1 vaccine virus, a widely used vaccine strain for mass vaccination programs against Peste des petits ruminants. J Gen Virol 83:1157–1165View ArticlePubMedGoogle Scholar Iwasa T, Suga S, Qi L, Komada Y (2010) Apoptosis of human peripheral blood mononuclear cells by wild-type measles virus infection is induced by interaction of hemagglutinin protein and cellular receptor, SLAM viacaspase-dependent pathway. Vet Res 46:15View ArticlePubMedPubMed CentralGoogle Scholar Manjunath S, Mishra BP, Mishra B, Sahoo AP, Tiwari AK, Rajak KK, Muthuchelvan D, Saxena S, Santra L, Sahu AR, Wani SA, Singh RP, Singh YP, Pandey A, Kanchan S, Singh RK, Kumar GR, Janga SC (2017) Comparative and temporal transcriptome analysis of peste des petits ruminants virus infected goat peripheral blood mononuclear cells.