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Abstract
Destructive changes in the hard and soft tissues have been reported in patients with maxillary complete denture opposed by natural anterior teeth and a bilateral distal extension removable partial denture. The characteristic features of these changes include loss of bone from anterior portion of the maxillary ridge, overgrowth of the tuberosities, papillary hyperplasia of hard palatal mucosa, extrusion of mandibular anterior teeth and loss of alveolar bone and ridge height beneath the mandibular removable partial denture bases, which is termed as combination syndrome as described by Kelly. This article reviews about sequelae of combination syndrome and recent treatment modalities in treating combination syndrome.
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