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Introduction
Ovarian cancer is a common malignant tumor in women. In recent years, the incidence of ovarian cancer is increasing and shows younger trend, and its mortality is the highest among gynecological malignancies (1). Bilateral ovarian resection is an important therapy for ovarian cancer, but the operation will sharply decrease estrogen in patients, increase osteoclastogenesis and inhibit bone absorption, leading to the reduction of patients' bone density and resulting in osteoporosis (OP) (2). Fracture easily occurs in OP patients, and the spine bears most of the stress, so vertebral compression fractures are the most common, which is known as osteoporotic vertebral compression fractures (OVCFs) (3). The clinical symptoms of OVCF patients after bilateral ovarian resection are not typical at the initial stage. It is difficult to arouse the attention of patients, but it will lead to spinal deformity over time, and eventually bring great pain to the patients, which not only brings heavy financial burden to the family, but also directly affects the quality of life of patients, so it should be paid great attention (4). OVCFs are clinically administered by conservative treatment and surgical treatment; therein, percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP), these two minimally invasive surgery modes, are mainly utilized at present, which display remarkable clinical efficacies, and the latter is developed on the basis of the former (5). In this study, patients with OVCFs after bilateral resection of ovarian cancer were treated with PVP and PKP, and the efficacy and safety of two surgical procedures were analyzed, so as to provide basis for the treatment of OVCFs, which is reported as follows.
Materials and methods
Clinical data
Eighty six patients with OVCFs after bilateral resection of ovarian cancer admitted to the Second People's Hospital of Hefei (Hefei, China) from September, 2015 to August, 2016 were selected. Inclusion criteria: i) Patients received bilateral resection of ovarian cancer; ii) OVCFs were diagnosed by X-ray examination; iii) bone density examination showed T <-2.5; and iv) patients signed the written informed consent. Exclusion criteria: i) Patients with severe osteomalacia or osteoporosis; and ii) patients with coagulation disorders. The enrolled patients were divided into observation group (n=43) and control group (n=43) using a random number table. The differences in general data of patients between the groups...