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Abstract
Glandular odontogenic cyst (GOC) is a rare developmental odontogenic cyst of the oral cavity. The most common site of occurrence for GOC is a mandibular anterior region, presenting typically in the middle age and has a minor male predilection. This article presented a case of GOC and focused on the review of clinico-pathologic features of the lesions considered in the differential diagnosis. A 17-year-old female patient reported with pain and swelling in the right upper front tooth region since 8 months. Radiographically, a well-defined unilocular radiolucency is seen in relation to impacted right maxillary canine. A provisional diagnosis of the dentigerous cyst was given. The excised tissue revealed a stratified squamous epithelial lining exhibiting cuboidal cells with goblet cells which are numerous and foci of epithelial cells presenting with eosinophilic material resembling mucin. The present case was associated with an impacted maxillary canine, which is found to be a very rare location for GOC. Thus, this case report of GOC will add to the existing knowledge of rare cysts.
Keywords: Canine, glandular odontogenic cyst, impacted tooth, mucous cells
Introduction
Glandular odontogenic cyst (GOC) is a rare developmental odontogenic cyst. Padayachee and Van Wyk reported the first case of the cyst as a "sialo-odontogenic cyst" in 1987. This cyst was further recognized as a distinctive entity by Gardner et al., in 1988, as "GOC."[1]
Clinically, the most common site of occurrence for GOC is a mandibular anterior region (88%), seen most commonly as an asymptomatic slow growing swelling. GOC occurs typically in the middle age (40-60 years) and has a slight male predilection. Radiologically, they might show unilocular or multilocular radiolucency with a distinct border.[2]
Histologically, GOC is characterized by a cystic lining of non-keratinized epithelium, mucous filled clefts, with papillary projections, nodular thickenings, and "mucous lakes." It also includes vacuolated cuboidal basal cells.[3]
Treatment of GOC includes enucleation with curettage and although a number of authors consider marginal resection to be added dependable treatment, due to the propensity of the cyst to recur following curettage and enucleation. Recurrences were seen in 30% of the cases.[4]
This article presented a case of GOC and focused on the review of clinico-pathologic features of the lesions considered in the differential diagnosis.
Case Report
A 17-year-old female...