The Synthesis of GoldMag Nano-Particles and their Application for Antibody Immobilization

Abstract

Fe₃O₄/Au (GoldMag) particles with core/shell structure were synthesized by reduction of Au³⁺ with hydroxylamine in the presence of Fe₃O₄. The synthesized particles have an average size smaller than 100 nm in diameter with of superparemagnetic properties due to their Fe oxide cores. The particles show optical features with a plasmon resonance peak from 550, 570 to 590 nm correlating with increasing diameters from 50 nm, 70 nm to 100 nm.The GoldMag particles need only a single step for antibody immobilization and have high binding capacity for antibodies. These advantages permit improved methods of isolating and detecting biomolecules.