Abstract

In situ squamous cell carcinoma of the skin (SCCis or Bowen's disease) is a common intraepidermal cutaneous malignancy with a low invasive potential. Acral Bowen's disease is usually solitary, but multiple acral SCCis have been reported. Pigmented Bowen's disease is typically unilesional and characterized by a hyperpigmented plaque with a velvety of keratotic surface, which can eventually simulate melanoma clinically. We describe two HIV-positive patients who presented with multiple pigmented SCCis involving the distal extremities. In patients with immunosuppression, the presence of multiple and hyperpigmented verrucae that clinically do not respond to adequate treatment should raise the differential diagnosis of SCC in situ.

Details

Title
Acral and multicentric pigmented Bowen's disease in HIV-Positive patients: Report on two unusual cases
Author
Fernandez-Sanchez, Monica 1 ; Charli-Joseph, Yann 2 ; Domínguez-Cherit, Judith 2 ; Guzman-Herrera, Saul 1 ; Reyes-Terán, Gustavo 1 

 Centro De Investigación En Enfermedades Infecciosas, Instituto Nacional De Enfermedades Respiratorias, Ismael Cosío Villegas, México City 
 Department of Dermatology, Instituto Nacional De Ciencias Médicas Y Nutrición Salvador Zubirán, México City 
Pages
506-508
Publication year
2018
Publication date
Nov/Dec 2018
Publisher
Medknow Publications & Media Pvt. Ltd.
ISSN
00195154
e-ISSN
19983611
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2129818516
Copyright
© 2018. This work is published under https://creativecommons.org/licenses/by-nc-sa/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.