Abstract

Candida auris is an emergent fungal pathogen that is resistant to multiple antifungals. Here, Muñoz et al. analyse genomic sequences for isolates from each of the four major C. auris clades and for three related species, and identify genetic features associated with virulence, antifungal resistance and mating.

Details

Title
Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species
Author
Muñoz, José F 1   VIAFID ORCID Logo  ; Gade, Lalitha 2 ; Chow, Nancy A 2 ; Loparev, Vladimir N 3 ; Juieng, Phalasy 3 ; Berkow, Elizabeth L 2 ; Farrer, Rhys A 1   VIAFID ORCID Logo  ; Litvintseva, Anastasia P 2 ; Cuomo, Christina A 1   VIAFID ORCID Logo 

1  Broad Institute of MIT and Harvard, Cambridge, MA, USA 
2  Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA 
3  Biotechnology Core Facility Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA 
Pages
1-13
Publication year
2018
Publication date
Dec 2018
Publisher
Nature Publishing Group
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1038/s41467-018-07779-6
ProQuest document ID
2157865849
Copyright
© 2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.