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Abstract
The PROPER trial (PERC Rule to Exclude Pulmonary Embolism in the Emergency Department) [5] is the frst randomized clinical trial that has its objective to prospectively validate the safety of PERC in ruling out PE by assessing the percentage of failures of this diagnostic strategy. This is a non-inferiority, crossover cluster-randomized clinical trial carried out in 14 France emergency departments (ED) during the period August 2015–September 2016. The follow-up period ended in December 2016. Patients with a low clinical probability of PE were included.
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; Quatela, Valentina 2 ; Moffat, Jane 3 ; Barbara Brignolo Ottolini 2 1 Scuola di Specializzazione in Medicina Interna, Università degli Studi di Milano, Milan, Italy
2 UOC Pronto Soccorso e Medicina d’Urgenza, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy
3 School of Medicine, Keele University, Newcastle upon Tyne, UK





